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Duodenal resurfacing achieves metabolic benefits in type 2 diabetes
SAN DIEGO – Thermal ablation of mucosal cells in the duodenum reduced hemoglobin A1c and liver enzyme levels.
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Factors identified for optimizing infliximab dosing in IBD
SAN DIEGO – A pharmacokinetic study showed for the first time that pre–anti-TNF exposure influenced the clearance of infliximab.
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Novel drug shows preclinical success in pancreatic cancer
SAN DIEGO – Based on studies in mice, the signals are promising for Metavert, a new drug for pancreatic cancer.
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Colorectal cancer threatens younger people
Health care providers should be alert for symptoms of colorectal cancer in younger patients, and encourage screening if symptoms are present.
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Gas-filled gastric balloons achieve weight loss
A system that utilizes gas-filled gastric balloons helped obese people lose almost twice as much weight, compared with lifestyle modifications.
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Low-residue diet enables clean colonoscopy
Eating small portions of low-residue foods on the day before colonoscopy improves visualization of the colon and patients’ comfort levels.
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Naldemedine improves opioid-induced constipation
SAN DIEGO – A cousin of naltrexone significantly improved all parameters of opioid-induced constipation in patients with chronic noncancer pain....
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Methylated DNA markers hold promise for Lynch syndrome
Methylated DNA markers (MDMs) have several advantages that are helpful for Lynch syndrome.
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Fecal transplanting effective in ulcerative colitis
A technique that is used to treat C. difficile infection reduced symptoms of ulcerative colitis and healed the digestive tract lining.
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Race predicts poor outcomes in people with liver cancer
Race was the strongest predictor of outcome in patients with hepatocellular carcinoma.
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Fecal bacteria plus FIT promising in diagnosis of colorectal cancer
SAN DIEGO – Researchers have identified a panel of four fecal bacteria that appear to identify colorectal cancer early.
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Tacrolimus worsens IBD post liver transplant for primary sclerosing cholangitis
SAN DIEGO – Recurrent PSC, prolonged use of steroids, and development of cancer after liver transplant were associated with a milder course of IBD...
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Acid suppression appears to prevent cancer in Barrett’s esophagus
A large study suggests that use of PPIs and H2RAs reduces the risk of progressing to cancer in patients with Barrett’s esophagus.
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Bile salts may be biomarker for recurrent C. difficile infection
First in-human evidence suggests that bile salts may be a biomarker for recurrent C. difficile infection.