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AGA Clinical Practice Update: Screening and surveillance for hepatocellular carcinoma in patients with NAFLD
Physicians should consider liver cancer screening for all patients with nonalcoholic fatty liver disease and cirrhosis.
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GERD symptoms affect one in three Americans
In all, 54% of patients on PPIs reported having breakthrough symptoms of heartburn or regurgitation.
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Study eyes gastric cancer predictors in Lynch syndrome
Risk factors included older age, male sex, family history, and having pathogenic variants in MLH1 or MSH2.
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Belapectin misses endpoints in NASH trial
A post-hoc subgroup analysis suggested a benefit for patients without esophageal varices.
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Pancreatic enzyme replacement flunked randomized trial
Low adherence was a factor.
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Testing phagocytes might better characterize IBD dysbiosis
The method characterizes bacteria closely associated with inflamed tissue.
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Trial of epicutaneous immunotherapy in eosinophilic esophagitis
The per-protocol analysis suggested that there was a lower eosinophil count with active treatment. .
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Eradicating H. pylori may cut risk of gastric cancer
Treatment without eradication was associated with an increase in risk.
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Long-term entecavir looks safe, effective in HBV
The entecavir and nonentecavir trial arms did not significantly differ in time-to-event analyses of malignant neoplasms, liver-related HBV disease...
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Gastric electrical stimulation device may improve refractory vomiting
However, gastric electrical stimulation did not significantly improve the coprimary endpoint of quality of life.
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Postcolonoscopy colorectal cancers had unique features
Their predisposition to the proximal colon and to microsatellite instability suggests that they have unique characteristics of tumorigenesis.
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Level of hepatitis B core–related antigen is risk factor for hepatocellular carcinoma
Compared with patients whose HBcrAg level was less than 10 KU/mL, a level of 10-99 KU/mL was associated with a nearly threefold increase in risk...
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Daily aspirin might cut risk of fibrosis progression
The researchers did not find a similar protective effect for NSAIDs other than aspirin.
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Threshold for positivity affects FIT sensitivity for detecting CRC, advanced adenomas
Specificity varied together with positivity thresholds, but less substantially than sensitivity.
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AGA Clinical Practice Update: Coagulation in cirrhosis
Consider alternatives to blood products to mitigate the risk of worsening portal hypertension, infection, and immunologic complications.