News
Dupilumab may reduce dysphagia in adults with eosinophilic esophagitis
- Author:
- Andrew D. Bowser
Results of phase 2 study show improvements in histologic, endoscopic, and patient-reported dysphagia outcome measures.
News
In older patients with immune-mediated TTP, atypical features may delay diagnosis
- Author:
- Andrew D. Bowser
Thrombocytopenia with anemia should alert physicians to this possible rare diagnosis in older patients with nonspecific neurological abnormalities...
News
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Treatment guided by remote readings works when used as intended
- Author:
- Andrew D. Bowser
PHILADELPHIA – No difference with traditional intent-to-treat analysis, but heart failure hospitalizations were...
Article
![](https://cdn-uat.mdedge.com/files/s3fs-public/styles/max_width_small/public/Chitturi_Kalyan_R_HOUSTON_web.jpg)
Cardiotoxicity after checkpoint inhibitor treatment seen early, linked to elevated biomarkers
- Author:
- Andrew D. Bowser
PHILADELPHIA – The findings support monitoring of cardiac biomarkers in the initial phase of checkpoint inhibitor treatment to identify patients...
News
Machine learning–derived risk score predicts heart failure risk in diabetes patients
- Author:
- Andrew D. Bowser
Highest WATCH-DM scores linked to 5-year heart failure risk approaching 20%.
News
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Milrinone beats dobutamine in extending survival in HF
- Author:
- Andrew D. Bowser
PHILADELPHIA – Survival benefit favored milrinone regardless of indication for use in continuous outpatient intravenous inotropic therapy.
News
Clinical trial enrollment linked to lower death rate in lung cancer patients
- Author:
- Andrew D. Bowser
ALEXANDRIA, VA. – Access to promising agents, enhanced supportive care, or both could provide direct patient benefit.
News
Out-of-pocket cost of oral TKIs linked to poor lung cancer survival
- Author:
- Andrew D. Bowser
ALEXANDRIA, VA. – If confirmed in a nationally representative study, findings could have implications for health policy and oncology practice.
News
Pyrotinib bests lapatinib in HER2+ metastatic breast cancer treatment
- Author:
- Andrew D. Bowser
The pan-ErbB inhibitor pyrotinib plus capecitabine had manageable toxicity, a significantly higher ORR, and significantly longer PFS, compared...
News
HIV drug may enhance efficacy of chemoradiation in locally advanced lung cancer
- Author:
- Andrew D. Bowser
Strategy incorporating protease inhibitor nelfinavir yields promising efficacy, acceptable toxicity in locally advanced non–small cell lung cancer...
News
PCSK9 inhibition cuts events in very-high-risk groups
- Author:
- Andrew D. Bowser
ODYSSEY OUTCOMES analyses peg prior CABG and polyvascular disease as targets for alirocumab.
News
Pretreatment CT data may help predict immunotherapy benefit in ovarian cancer
- Author:
- Andrew D. Bowser
Fewer sites of disease and lower intratumor heterogeneity on contrast-enhanced CT may indicate a higher likelihood of durable response to immune...
News
Recurrence score may help predict chemotherapy benefit in grade 3 breast cancers
- Author:
- Andrew D. Bowser
In data that complement the TAILORx findings, chemotherapy was not linked with significantly improved OS for those with a low recurrence score...
News
![](https://cdn-uat.mdedge.com/files/s3fs-public/styles/max_width_small/public/gene_mutation_web.jpg)
USPSTF expands BRCA1/2 testing recommendations
- Author:
- Andrew D. Bowser
Personal cancer history, ancestry now key factors in decision to assess, counsel, and test for potentially harmful mutations in BRCA1/2 genes.
News
Post-TAVR anticoagulation alone fails to cut stroke risk in AFib
- Author:
- Andrew D. Bowser
By contrast, antiplatelet therapy linked to reduced risk of stroke, whether or not oral anticoagulation was used in this PARTNER II substudy.