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SAFE algorithm detects liver disease in general population
Scoring system was developed and validated to detect clinically significant (greater than stage 2) fibrosis in patients with NAFLD in primary care...
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‘Exciting time for NASH’ with resmetirom phase 3 results
Two doses of resmetirom met the primary endpoints of NASH resolution and no worsening of fibrosis on liver biopsy.
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New EULAR lupus recommendations advise using biologics, tapering steroids
The 2023 recommendations cover new treatment strategies with more ambitious goals, new data on adverse effects of chronic glucocorticoid use, and...
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Investigational uricase-based gout drug meets primary endpoints in phase 3 trials
Two phase 3 trials of the once-monthly SEL-212 in refractory gout achieved and maintained serum uric acid < 6 mg/dL for ≥ 80% of the final...
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EULAR systemic sclerosis recommendations now include immunosuppressants
The update to 2017 recommendations include targeted synthetic and biologic DMARDs for the first time.
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URAT1 inhibitor shows ‘substantial’ uric acid reduction in phase 2 gout trial
The investigational drug, AR882, reduced serum uric acid to levels seen in people without hyperuricemia and gout.
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Encouraging telitacicept results reported in phase 3 for lupus, phase 2 for Sjögren’s
Results of a phase 3 trial in Chinese patients with systemic lupus erythematosus showed a significantly greater response rate with telitacicept,...
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ILD risk elevated in RA, PsA after starting biologic or targeted synthetic DMARDs
The risk for interstitial lung disease in patients with PsA during the first 5 years after starting a biologic or targeted synthetic DMARD was...
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Tweaking food delivery apps can lower calories purchased
“These studies provide encouraging proof-of-concept evidence that small tweaks in delivery apps could help many people to identify and select...
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‘Staggering’ weight loss and benefits in body composition with tirzepatide
“Something we have sought for decades, we have finally been able to achieve.”
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Ear acupuncture with diet aids weight loss
Acupuncture beads, used in Japan to augment weight loss for more than 30 years, are thought to stimulate nerves and organs that regulate appetite...
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Half of teens drop below obesity cutoff with semaglutide
The semaglutide findings are “historically unprecedented with treatments other than bariatric surgery.”
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Obesity drug with swallowable balloon boosts weight loss
“In Europe, use of the swallowable gastric balloon is common, the results are good, and it is a safe tool.”
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Metabolic abnormalities boost obesity-related cancer risk
“A significant number of cancer cases could potentially be prevented by targeting the coexistence of metabolic problems and obesity, in particular...