Article
Ebola—lessons still to be learned
- Author:
- Brian F. Mandell, MD, PhD
So far, the disease has barely touched our country, but it has had a big impact on our health care system and our national psyche.
Article
Screening guidelines: A matter of perspective
- Author:
- Brian F. Mandell, MD, PhD
Guidelines are only guidelines: We should use them within a personalized context.
Article
To dream the maybe possible dream: A breast cancer vaccine
- Author:
- Brian F. Mandell, MD, PhD
The work is in an extremely preliminary phase, but the concept is an active area of research worth keeping tabs on.
Article
Polycystic kidney disease: Molecular understanding dictating management
- Author:
- Brian F. Mandell, MD, PhD
It was the early 1980s, I was a resident in the emergency room, and the patient had fever, flank pain, hypotension, and a normal urinalysis.
Article
When snoring is more than an annoyance
- Author:
- Brian F. Mandell, MD, PhD
We should vigilantly look for obstructive sleep apnea and, if it is diagnosed, strongly encourage treatment.
Article
Smart testing: An old idea, a new series
- Author:
- Brian F. Mandell, MD, PhD
We hope to change test-ordering behaviors in situations in which there is a smart—and a not-so-smart—way to pursue a diagnosis.
Article
COPD: More options mean potentially better control
- Author:
- Brian F. Mandell, MD, PhD
Although newer drugs can improve control, to make the biggest impact on mortality we need to wage war on smoking.
Article
The generalist, the specialist, and the patient with chronic kidney disease
- Author:
- Brian F. Mandell, MD, PhD
Comanagement of patients who have a chronic disease is often a challenge.
Article
Appreciating the appetite for reflective practice
- Author:
- Brian F. Mandell, MD, PhD
Twenty-five years later, I still think about eating disorders when I evaluate young women who have severe fibromyalgia.
Article
New practice guidelines: Constrained or enhanced by the evidence?
- Author:
- Brian F. Mandell, MD, PhD
The new guidelines on cholesterol and hypertension are more evidence-based, but will they help improve outcomes?
Article
The impact of anti-TNF therapy on the nonspecialist
- Author:
- Brian F. Mandell, MD, PhD
These drugs are being used in a growing number of diseases. We all need to increase our familiarity with their unique risks.
Article
Should patients with gout avoid thiazides for hypertension?
- Author:
- Brian F. Mandell, MD, PhD
No study has directly addressed this issue. In most cases, continue the thiazide and adjust the hypouricemic therapy if necessary.
Article
Return of the 'pisse-mongers,' this time with data
- Author:
- Brian F. Mandell, MD, PhD
Urinalysis may be the oldest surviving laboratory test. Both Hippocrates and Galen recognized its value.
Article
To Phil, adieu with many thanks and much gratitude
- Author:
- Brian F. Mandell, MD, PhD
Phil Canuto, the executive editor of the Cleveland Clinic Journal of Medicine for almost 20 years, is retiring.
Article
When people with diabetes go to surgery
- Author:
- Brian F. Mandell, MD, PhD
A key take-home point is that severely insulinopenic patients require some exogenous basal insulin, even when not eating.