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Living donor liver transplants on rise for most urgent need
Patient survival appears to be comparable to deceased donor liver transplantation.
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Pediatric celiac disease incidence varies across U.S., Europe
“From a policy standpoint, this informs future screening practices and supports efforts toward mass screening, at least in some areas.”
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NAFLD patients with diabetes have higher fibrosis progression rate
Patients with type 2 diabetes had about a 2-year faster progression to fibrosis.
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Noninvasive tests may provide prognostic value in NAFLD
Fibrosis biomarkers were significantly predictive of event-free survival probability.
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Low-carb diet aids weight loss in liver transplant recipients with obesity
The diet didn’t negatively affect serum lipids or renal function.
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Don’t wait for patients to bring up their GI symptoms
A third of patients said they didn’t know if their symptoms are a problem, and more than a quarter said they would wait until their condition...
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Endoscopic severity score helps guide treatment in immune-mediated colitis
The scoring system could assist with accurate severity assessment and choice of medical treatment.
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Guselkumab induction improves moderate to severe active UC at week 12
The drug was statistically superior to the placebo across all key endpoints in phase 2b study, regardless of patient response or intolerance to...
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Dupilumab improves eosinophilic esophagitis up to 24 weeks
The drug received FDA approval for EoE treatment earlier in 2022.
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Major U.S. GI societies issue strategic plan on environmental sustainability
Individual and group efforts can help mitigate the effects of climate change on digestive health and health care systems.
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Latiglutenase reduces symptoms in celiac patients exposed to gluten
The investigational dual-enzyme drug appears to attenuate gluten-induced intestinal mucosal damage.
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Terlipressin decreases need for renal replacement therapy in liver transplant recipients
The drug restores renal blood flow and reverses hepatorenal syndrome type 1 in some patients.
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Pancreatic cancer screening appears safe, effective for high-risk patients
The study explored a targeted strategy for screening since pancreatic cancer screening is not recommended for the general population.
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Children with asymptomatic celiac disease may have severe disease histology
A new report emphasizes the importance of celiac disease screening for all children with affected first-degree relatives, as symptom status may...
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Vedolizumab linked to increased treatment failure in older patients with Crohn’s
Findings indicate that vedolizumab is associated with an increased risk for treatment failure in older patients with inflammatory bowel disease (...