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PAM50-based score identifies low-risk subset with node-positive early-stage breast cancer
About 37% of patients with a single positive lymph node and 15% of patients with two positive nodes were identified as low risk, with very...
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CLL Index proves accurate in predicting survival, time to treat
A meta-analysis shows that the CLL-IPI is a useful tool with chemoimmunotherapy, but data is lacking about its use with targeted therapies.
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Hodgkin lymphoma survivors are at an increased risk of subsequent ER-negative breast cancer
Subsequent risk of estrogen receptor–negative breast cancer was elevated irrespective of the type of therapy given for Hodgkin lymphoma.
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Retroperitoneal lymphadenectomy did not impact OS and DFS for high risk, nonmetastatic renal cell carcinoma
In a secondary analysis of the ASSURE adjuvant trial, there was no relative improvement in overall survival for lymphadenectomy in high-risk RCC...
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Analysis of Twitter lung cancer content reveals opportunity for clinicians
Twitter conversations focused on treatment and end of life were significantly less likely to integrate cues for personal activity.
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OS similar among mRCC patients enrolled in clinical trials across different geographic regions
Despite different baseline characteristics, OS was similar among patients enrolled in clinical trials across different geographic regions.
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Refractory FGFR-altered cholangiocarcinoma responds to FGFR kinase inhibitor
A median progression-free survival of 5.8 months is encouraging in patients with this aggressive cancer, and this targeted therapy warrants...