Article
Does hormone replacement therapy prevent cognitive decline in postmenopausal women?
EVIDENCE-BASED REVIEW: NO. Hormone replacement therapy (HRT) does not prevent cognitive decline in postmenopausal women—and in fact, it may...
Article
Do behavioral interventions improve nighttime sleep in children < 1 year old?
EVIDENCE-BASED ANSWER: YES. Infants respond to behavioral interventions, although objective data are limited. Behavioral interventions include...
Article
Antibiotics and COPD: Time to order a C-reactive protein test?
Consider C-reactive protein–guided prescribing of antibiotics in acute chronic obstructive pulmonary disease exacerbations in the outpatient...
Article
Is NPH associated with fewer adverse events than analog basal insulin for adults with T2D?
EVIDENCE-BASED ANSWER: NO. Insulin glargine may lead to less patient-reported, symptomatic, and nocturnal hypoglycemia, although overall, there...
Article
Consider this Rx for patients with high triglycerides?
A daily dose of this prescription fish oil may be worth a trial in light of the cardiovascular benefits it affords statin-treated patients with...
Article
Do-it-yourself cervical cancer screening?
Enlisting patients to self-collect specimens for human papillomavirus testing is an effective way to detect cervical precancer in those who might...
Article
Immediate or delayed pushing in the second stage of labor?
Is there any advantage to delaying pushing in the second stage of labor for nulliparous women receiving epidural analgesia?
Article
Aspirin, Yes, for at-risk elderly—but what about the healthy elderly?
This study paints a decidedly different picture as to what role—if any—aspirin can play in the primary prevention of CVD for older adults.
Article
What is the best treatment for wrist ganglion cysts?
EVIDENCE-BASED ANSWER: Open surgical excision of wrist ganglion cysts is associated with a lower recurrence rate than aspiration with or without...
Article
Do Probiotics Reduce C diff Risk in Hospitalized Patients?
A systematic review and meta-analysis says, “Yes,” but that doesn’t necessarily mean they will start appearing on hospital...
Article
Should You Switch the DAPT Agent a Month After ACS?
A randomized controlled trial says “Yes,” but current guidelines say “No.”
Article
Do probiotics reduce C diff risk in hospitalized patients?
A systematic review and meta-analysis says, “Yes,” but that doesn’t necessarily mean they will start appearing on hospital formularies.
Article
How effective is spironolactone for treating resistant hypertension?
EVIDENCE-BASED ANSWER: Very effective. Spironolactone reduces systolic blood pressure (SBP) by 11 to 17 mm Hg and diastolic blood pressure (DBP)...
Article
Less Is More When It Comes to Ketorolac for Pain
It’s time to review our dosing with ketorolac for acute pain management.
Article
What are the risks of long-term PPI use for GERD symptoms in patients > 65 years?
EVIDENCE-BASED ANSWER: The use of proton pump inhibitors (PPIs) to control gastroesophageal reflux disease (GERD) is significantly associated with...