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What is the proper treatment for posttraumatic headache? Expert debate
Preventative treatment could reduce chronification, but has the potential to worsen comorbidities.
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Prodrome treatment with ubrogepant prevents migraines
Intervention also reduced prodromal symptoms in patients who could reliably predict oncoming headaches.
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Migraine treatment with rimegepant linked to reduced barbiturate use
Real-world analysis suggests potential for improvements in medication overuse and dependency.
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Migraine device expands treatment possibilities
New studies of remote electrical neuromodulation show efficacy in adolescents and safety during pregnancy.
Article
Cannabis RCT shows efficacy, AEs in migraine
First RCT in migraine suggests THC/CBD mix might be best, and that recreational doses may be higher than necessary.
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Migraine clusters emerge from machine-learning analysis
Groupings somewhat reflect expert consensus, but also suggest therapeutic avenues.
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New study backs up capecitabine dosing practice in metastatic BC
Study finds similar progression-free and overall survival in 7-day-on/7-day-off schedule, with fewer side effects than 14 days on, 7 days off.
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In TNBC, repeated biopsies may reveal emergent HER2-low expression
Results could broaden eligibility for treatment with the antibody-drug conjugate trastuzumab deruxtecan.
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ER+/HER2– breast cancer: Is first or second line CDK4/6 inhibitor therapy better?
New study challenges the need for using CDK4/6 inhibitors as first line treatment, according to author.
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Review may help clinicians treat adolescents with depression
“We did two systematic reviews to look at the continuing professional development of family physicians in adolescent health, and it turned out...
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Metronomic chemotherapy performs well in second-line head and neck cancer
Lower-dose therapy granted PFS and OS gains, with fewer side effects, compared with standard chemotherapy options.
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Antibody-drug conjugate changes standard of care for platinum-resistant ovarian cancer
A novel therapy has a favorable safety profile, and more like it may be on the way.
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SCLC: Bispecific antibody shows phase 1 promise
The antibody targets delta-like ligand 3, which is one of few surface markers for small cell lung cancer.
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Surgical de-escalation passes clinical test in low-risk cervical cancer
‘Practice-changing’ results could reduce long-term survivor effects among qualifying patients.
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Stem cell transplants are more effective than some MS therapies
The results of the new study are “encouraging,” but plenty of unanswered questions remain.