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VIDEO: Poorer cardiometabolic health seen in men with low sperm count
The cardiometabolic derangement was seen even in men with normal testosterone levels.
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Posttransplant cyclophosphamide helped reduce GVHD rates
SALT LAKE CITY – The GVHD prophylaxis regimen had better survival rates than those of the tacrolimus-methotrexate control group.
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Ibrutinib preserves immune memory while fighting cGVHD
SALT LAKE CITY – The data come from a phase 1/2 trial of ibrutinib as second-line therapy for chronic graft versus host disease.
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Metformin reduces preterm births, late miscarriages in PCOS
The “elephant in the room” was the lack of benefit for gestational diabetes.
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VIDEO: Intestinal remodeling contributes to HbA1c drop after Roux-en-Y gastric bypass
Gene expression at 1 month tracked with HbA1c levels out to 1 year post surgery.
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Think about breast cancer surveillance for transgender patients
CHICAGO - In transgender men, breast cancer can occur years after mastectomy.
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Most patients off transfusions after gene therapy for thalassemia
SALT LAKE CITY – As the vector copy number goes up, so does the likelihood of stopping transfusions.
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VIDEO: Adipogenic genes upregulated in high-BMI sucralose users
The effects, which parallel those of glucose, were much less marked in normal-weight individuals.
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VIDEO: Women living with HIV have more myocardial steatosis, reduced diastolic function
The investigators found an inverse relationship between myocardial triglycerides and diastolic function.
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Low microbiota diversity linked to poor survival after transplant
SALT LAKE CITY - Lower calorie intake and exposure to broad-spectrum antibiotics were both associated with lower microbiota diversity.
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VIDEO: Fezolinetant drops testosterone levels in PCOS
CHICAGO – The NK3R antagonist met the primary endpoint, but a longer trial may be needed to see fertility climb.
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Balance risk with reality for pre-conception diabetic counseling
CHICAGO – Early rapport-building can go a long way with pregnant patients.
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High-normal TSH linked to unexplained infertility
CHICAGO – TSH levels in the top half of the normal range were twice as common in this group.
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CAR T before transplant yields durable remission in B-cell malignancies
SALT LAKE CITY – The analysis also showed the value of next-generation sequencing in detecting relapse earlier than flow cytometry can.
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Nonmyeloablative conditioning gets a radiation boost for severe hemoglobinopathies
SALT LAKE CITY – Doubling total body irradiation reduced graft rejection without increasing toxicity for patients with sickle cell disease or beta...