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Lower-dose FOLFIRINOX effective, safer for pancreatic cancer
“The best dose modification protocol” remains to be determined and standardized for metastatic pancreatic cancer.
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Was the fruquintinib trial for metastatic CRC a win?
“One could debate if 2.6 months of more time is worth the medication getting regulatory approval, or debate pricing when it’s approved, or delve...
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No benefit to adding limited radiation in advanced cancer
Median overall survival was not significantly better with radiotherapy, compared with the control group, nor was the objective response rate.
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Diabetes may short circuit pembrolizumab benefits in NSCLC
"There is an urgent need to validate our findings and explore whether outcomes in these patients can be improved by better glycemic control."
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FDA approves first gene therapy for hemophilia A
The expensive, one-time, single-dose IV infusion for severe hemophilia A may offer patients years of freedom from infusions.
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MRI identifies rectal cancer patients who can skip CRT
Study suggests that neoadjuvant chemoradiation therapy can be restricted to patients at high risk of locoregional recurrence.
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Breast cancer family history linked to better BC survival
A family history of breast cancer was associated with a lower risk of breast cancer-specific death, after adjustments, a new study finds.
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No safe dose of cardiac radiation in children?
“These findings solidify the need to consider cardiac substructure doses in [pediatric] radiation treatment planning and in survivorship care.”
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‘New standard of care’ for capecitabine hand-foot syndrome
“For me as a GI oncologist, topical diclofenac for prevention of HFS for patients on capecitabine is practice changing,” ...
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Risk of falls seen with newer antiandrogens for prostate cancer
The take-home message is that the findings give men – and the physicians who counsel them – a fuller idea of what to expect when considering using...
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Safe to stop immunotherapy at 2 years in stable lung cancer
“These data may provide reassurance to us and patients that discontinuing treatment at 2 years can confer the same overall survival as extended...
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Oncologist pleads guilty to prescription drug fraud
Dr. Kachadourian was paid more than $170,000 for purchasing and allowing others to purchase in her name millions of dollars in prescription drugs...
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Warning on use of sotorasib after ICI in lung cancer
“We suggest avoiding starting sotorasib within 30 days from the last anti–PD-(L)1 infusion.”
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Posluma approved for PET imaging in prostate cancer
“The study showed that Posluma PET provided clinically valuable information prior to surgery that would likely result in management changes for...
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FDA approves epcoritamab for r/r DLBCL
Epcoritamab for adults with relapsed/refractory diffuse large B-cell lymphoma has been approved by the FDA.