Article
![Mouse monoclonal antibodies to type VII collagen followed by goat anti-mouse IgG–fluorescein isothiocyanate conjugate (original magnification ×200). Mouse monoclonal antibodies to type VII collagen followed by goat anti-mouse IgG–fluorescein isothiocyanate conjugate (original magnification ×200).](https://cdn-uat.mdedge.com/files/s3fs-public/styles/max_width_small/public/CT111006278_300x300.jpg)
Extensive Erosions and Ulcerations on the Trunk and Extremities in a Neonate
- Author:
- Julia L. Accetta, MD
- Saachvir Singh
- Raminder K. Grover, MD
- Matthew F. Helm, MD
A neonate was born with extensive erosions and ulcerations on the trunk and extremities. The eroded areas had a beefy red appearance. A biopsy...
Article
![Asymmetric pigmented macules and patches of genital lentiginosis in the vulva. Asymmetric pigmented macules and patches of genital lentiginosis in the vulva.](https://cdn-uat.mdedge.com/files/s3fs-public/styles/max_width_small/public/CT110004036_e_300x300.jpg)
Genital Lentiginosis: A Benign Pigmentary Abnormality Often Raising Concern for Melanoma
- Author:
- Nathan M. Albert, BS
- Andrew Gaddi, DO
- Meghan A. Klawonn, MD
- Leesha Helm, MD
- Matthew F. Helm, MD
The irregular appearance of genital lentiginosis—multifocal, asymmetric, irregular, and darkly pigmented patches—often raises concern for melanoma...
Article
Surgical Specimens and Margins
- Author:
- Thomas N. Helm, MD
- Matthew F. Helm, MD
- Klaus F. Helm, MD
Margin analysis in simple excisions can provide useful information by proxy about more than the 1% of the margin often quoted in the literature....
Article
![](https://cdn-uat.mdedge.com/files/s3fs-public/styles/max_width_small/public/CT106003142_300x300.jpg)
Rapid Onset of Widespread Nodules and Lymphadenopathy
- Author:
- Taylor E. Gladys, BA
- Matthew F. Helm, MD
- Bryan E. Anderson, MD
- Klaus F. Helm, MD
A 71-year-old man presented with an eruption on the face, shoulders, upper back, and arms of 3 weeks’ duration. A biopsy of an arm nodule...
Article
![](https://cdn-uat.mdedge.com/files/s3fs-public/styles/max_width_small/public/CT106003118_300x300.jpg)
Bullae and Hyperpigmented Patches on the Legs
- Author:
- Paul A. Regan, MD
- Bryan E. Anderson, MD
- Matthew F. Helm, MD
A 50-year-old man presented with a pruritic bullous dermatosis on the lower legs, arms, and back of 1 month’s duration. He had an 8-year history...
Article
![Plaque psoriasis Plaque psoriasis](https://www.qa.mdedge.com/sites/all/modules/contrib/lazyloader/image_placeholder.gif)
The many variants of psoriasis
- Author:
- Karl T. Clebak, MD, FAAFP
- Leesha Helm, MD, MPH
- Matthew F. Helm, MD
- Elizabeth V. Seiverling, MD
Erythema, skin thickening, and scales typify most cases, but other patterns exist. Tx choices may differ, depending on how much body surface area...
Article
![Erosions and ulcerations with hemorrhagic crust on the dorsum of hands and milia on knuckle pads Erosions and ulcerations with hemorrhagic crust on the dorsum of hands and milia on knuckle pads](https://www.qa.mdedge.com/sites/all/modules/contrib/lazyloader/image_placeholder.gif)
Chronic blistering rash on hands
- Author:
- Christopher G. Bazewicz, MD
- Matthew F. Helm, MD
- Jeffrey J. Miller, MD
The location of the patient’s lesions and multiple risk factors suggested that an uncommon disorder was at work.
Article
![Red, swollen, and tender ear Red, swollen, and tender ear](https://www.qa.mdedge.com/sites/all/modules/contrib/lazyloader/image_placeholder.gif)
Erythematous swollen ear
- Author:
- Meghan A. Klawonn, MD
- Melissa M. Helm
- Matthew F. Helm, MD
The timing of the reaction in this case led us to the proper diagnosis.
Article
![Progressive discoloration over the right shoulder Progressive discoloration over the right shoulder](https://www.qa.mdedge.com/sites/all/modules/contrib/lazyloader/image_placeholder.gif)
Progressive discoloration over the right shoulder
- Author:
- Matthew F. Helm, MD
- David Cole, MD
- Elizabeth V. Seiverling, MD
The discolored patch on our patient’s shoulder was nothing new—but when it grew in size and developed hypertrichosis, it prompted a closer...