News
Botox benefits in primary fascial closure questioned
Key clinical point: The use of Botox to induce flaccid paralysis of the abdominal wall muscles is of questionable value in achieving primary...
News
Peer pressure moves dial on restricting RBC transfusions
Key clinical point: Peer-to-peer review improves the use of restrictive transfusion guidelines without increasing mortality. Major finding: The...
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Trio of risk factors predict gangrenous cholecystitis
Key clinical point: Older age, diabetes and elevated bilirubin were risk factors for acute gangrenous cholecystitis. Major finding: Patients with...
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The private-academic surgeon salary gap: Would you pick academia if you stood to lose $1.3 million?
Key clinical point: Whether calculated as gross lifetime income or 5% net present value, a salary disparity exists between academic and private...
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Regionalized trauma care trims 30-day mortality
Key clinical point: Regionalized trauma care reduces long-term mortality and maintains functional outcomes in patients with severe TBI. Major...
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Checklist dramatically improves safety of bedside tracheostomy
Key clinical point: A multidisciplinary checklist before percutaneous bedside tracheostomy can improve adverse event rates and overall safety.
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Anti-CD38 antibodies poised to transform myeloma treatment
Key clinical point: The investigational anti-CD38 antibodies SAR650984 and daratumumab in combination with standard regimens were highly active in...
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CAR-T cell therapy rolls on in pediatric ALL
Key clinical point: CAR-T cell therapy continues to provide durable responses in early studies of children with refractory ALL. Major finding:...
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VALOR: Baby step forward or misstep in AML?
Key clinical point: Vosaroxin plus cytarabine failed to significantly improve overall survival in relapsed or refractory AML, but may offer older...
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Nursing home-onset C. difficile infections cut wide swath
Key clinical point: Nursing home-onset C. difficile infections are associated with significant morbidity and mortality. Major finding: An...
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ICD lead extraction complication rates warrant surgical backup
Key clinical point: Appropriate training and optimal cardiothoracic surgical backup is necessary at all centers performing lead extractions,...
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CABG plus mitral repair put under spotlight
Key clinical point: CABG plus mitral repair did not significantly improve left ventricular remodeling at 1 year, and was associated with some...