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Phase 3 trial: Tasimelteon effective for jet lag disorder
BALTIMORE – A phase 3 trial on a melatonin receptor agonist use for jet lag reported at Sleep 2018.
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CPAP and oxygen have different cardiac effects in OSA
BALTIMORE – Trial finds continuous positive airway pressure and supplemental oxygen for obstructive sleep apnea may have countering effects on ECG...
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Impact of marijuana on sleep not well understood
BALTIMORE – More research is needed on the impact of medical marijuana on sleep disorders.
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Sleep problems may point to health disparity for black women
BALTIMORE – A national study has found that black women are more vulnerable to sleep-related health problems than women of European descent.
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OSA with worsening hypoxemia raises metabolic syndrome risk
BALTIMORE – An 8-year follow-up study reports that moderate to severe sleep apnea more than doubles the risk of developing metabolic syndrome.
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Upping the game of surgical researchers
To elevate the science of surgical research, JAMA Surgery published a how-to series on large database analyses to guide potential authors.
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Enhanced recovery led to fewer complications for major oncologic procedures
CHICAGO – A study has found that enhanced recovery protocols are safe and feasible in major abdominal operations beyond colorectal surgery.
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Gene strong predictor of metastasis in melanoma
CHICAGO – Investigators have identified four genes that are overexpressed in primary melanoma, including one, CXCL1, that holds promise as a...
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Extracapsular spread predicts survival in SLN+ melanoma
CHICAGO – Extracapsular spread may be an important indicator of PFS and OS in sentinel node positive micrometastatic melanoma.
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How complications drive post-surgery spending upward
JACKSONVILLE, FLA. – Hospitals should look at reducing complications following surgery to contain costs.
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Study finds gaps in bundled colectomy payments
CHICAGO – Surgeons need to consider strategies to close potential gaps between charges for colectomy and Medicare bundled payments.
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Surgery after immunotherapy effective in advanced melanoma
CHICAGO – Five-year survival was 75% in selected patients with advanced melanoma who had resection to no evidence of disease after immunotherapy...
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Can cN0 and pCR limit axillary surgery in some breast cancer patients?
CHICAGO – Investigators question whether nodal negativity after neoadjuvant chemotherapy could limit need for axillary surgery in certain breast...
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No increased complication risk with delaying resection for LARC
CHICAGO – Surgical resection for locally advanced rectal cancer at up to 12 weeks after neoadjuvant therapy did not increase complication risk.
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Accuracy of colon cancer lymph node sampling influenced by location
CHICAGO – A multicenter trial shows that left-sided colon cancer requires sampling more lymph nodes than does right-sided disease for true nodal...