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Enthesitis, arthritis, tenosynovitis linked to dupilumab use for atopic dermatitis
Musculoskeletal symptoms identified in some patients treated with dupilumab for atopic dermatitis could help further understanding of how...
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Low disease state for childhood lupus approaches validation
A new childhood version of the Lupus Low Disease Activity State has been purposefully developed to align with the criteria already used for adults...
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Normal CRP during RA flares: An ‘underappreciated, persistent phenotype’
In about 5% of patients with seropositive RA, C-reactive protein levels were normal despite disease flares during a 5-year period. The findings...
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Long-COVID rate may be higher with rheumatic diseases
The results highlight the need for close monitoring and optimized multidisciplinary care for long-term adverse events after COVID-19 in patients...
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NSAID use may mask MRI findings in a quarter of spondyloarthritis cases
Among nearly one in four patients whose MRI results were initially positive for sacroiliitis, results were negative 6 weeks after NSAIDs were...
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Meta-analysis examines cancer risk concern for JAK inhibitors
Although no increased cancer risk was seen vs. methotrexate or placebo, Janus kinase inhibitors were associated with a higher cancer risk than...
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Registry data ‘reassure’ on biologics’ heart attack risk in rheumatoid arthritis
There is no difference in the risk of myocardial infarction with interleukin-6 (IL-6) vs. anti–tumor necrosis factor (TNF) therapy for rheumatoid...
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Cardiovascular risk score multipliers suggested for rheumatic diseases
Guidelines could tailor cardiovascular risk scores by using a multiplier of 2.5 for systemic sclerosis, 2.0 for lupus, and 1.5 for any other...
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RA risk raised by work-related inhaled agents
Exposure to detergents, dusts, and other chemicals in the workplace could be putting genetically susceptible people at risk of rheumatoid...
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Gestational hypertension-diabetes combo signals CVD risk
Having both hypertensive disorders and diabetes while pregnant ups later cardiovascular risk, suggesting greater care is needed when these...
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Rituximab raises remission rate in granulomatosis with polyangiitis
Remission at 6 months was recorded in 73.1% of rituximab-treated patients and 40.1% of cyclophosphamide-treated patients in a multicenter target...
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52-week data show lebrikizumab atopic dermatitis effects maintained
ADvocate1 and ADvocate2 are two of several phase 3 trials evaluating the efficacy and safety of lebrikizumab for the treatment of atopic...
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Ruxolitinib repigments many vitiligo-affected body areas
Ruxolitinib is a Janus kinase 1/2 inhibitor that has been available for the treatment for atopic dermatitis for more than a year.
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BREEZE-AD-PEDS: First data for baricitinib in childhood eczema reported
Treatment with the oral JAK inhibitor was significantly more effective than placebo only with the highest dose evaluated.
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Alopecia areata: Positive results reported for two investigational JAK inhibitors
“This is truly transformative therapy,” one of the investigators, Brett King, MD, PhD, said.