News
IRONMAN galvanizes case for IV iron repletion in heart failure
- Author:
- Steve Stiles
The trial missed its primary endpoint, but makes unique contributions; many see it as further evidence that the treatment helps iron-deficient...
News
Be aware, mindfulness training can lower systolic BP: MB-BP
- Author:
- Steve Stiles
“This is exactly what we need: a well-done trial with a control group to show that it actually works,” said one expert, cautioning that it...
News
Optimize HF meds rapidly and fully after hospital discharge: STRONG-HF
- Author:
- Steve Stiles
Outcomes were superior with a high-intensity up-titration strategy compared with usual care, but questions about implementation in practice remain...
News
Dietary supplements hyped as LDL cholesterol lowering are a bust: SPORT
- Author:
- Steve Stiles
The list of supplements without effects on LDL in the placebo-controlled trial include commercial preparations of fish oil, cinnamon, garlic,...
News
Avoid routine early ECMO in severe cardiogenic shock: ECMO-CS
- Author:
- Steve Stiles
Early ECMO in this setting is increasingly common, but it didn’t seem to improve outcomes in the trial, compared with a more conservative approach...
News
No survival advantage for either torsemide or furosemide in HF: TRANSFORM-HF
- Author:
- Steve Stiles
One loop diuretic is the most widely used in heart failure, the other may have advantages in some situations, but there’s been no head-to-head...
News
AHA 2022 to recapture in-person vibe but preserve global reach
- Author:
- Steve Stiles
Planners see the meeting’s Chicago return as a hybrid after 2 years relegated to cyberspace as a chance for first impressions on some just...
News
FDA OKs Medtronic lead for left bundle branch pacing
- Author:
- Steve Stiles
A lead already approved for stimulating the His bundle is now also indicated for LBB pacing, another prominent form of conduction system pacing....
News
Trial of early intensive meds at HF discharge halted for benefit: STRONG-HF
- Author:
- Steve Stiles
Topline results point to significant clinical benefit from a strategy featuring early initiation and rapid uptitration of meds for patients...
News
FDA approves self-administered, SubQ furosemide preparation
- Author:
- Steve Stiles
The preparation of the common loop diuretic is said to provide “intravenous-equivalent” dosing for outpatients with heart failure and volume...
News
Dapagliflozin DELIVERs regardless of systolic pressure in HFpEF
- Author:
- Steve Stiles
The finding may alleviate long-standing concerns that starting modestly diuretic SGLT2 inhibitors in patients with heart failure might present a...
News
Salt pills for patients with acute decompensated heart failure?
- Author:
- Steve Stiles
It may seem counterintuitive, but a new trial testing extra sodium intake in patients receiving high-dose intravenous diuretics for acute HF...
News
Add PCSK9 inhibitor to high-intensity statin at primary PCI, proposes sham-controlled EPIC-STEMI
- Author:
- Steve Stiles
The powerful LDL cholesterol–lowering agents aren’t being used to their fullest potential, but giving them early to STEMI patients along with high...
News
Legacy of neutral renal denervation trial recast by long-term outcomes: SYMPLICITY HTN-3
- Author:
- Steve Stiles
Although interest in renal denervation in hypertension fell off after disappointing results from the 2014 trial, a new, longer-term analysis...
News
PASCAL for MV repair noninferior to MitraClip in CLASP IID; FDA took notice
- Author:
- Steve Stiles
A newly FDA-approved transcatheter mitral valve repair system and another one widely used for years were similarly safe and effective in an...