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Bempedoic acid cuts CV events in statin-intolerant patients: CLEAR Outcomes
The CLEAR Outcomes trial establishes this new drug as an important addition to available nonstatin LDL cholesterol–lowering therapies, experts say...
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New AHA statement urges focus on CV risk before pregnancy
The emphasis on reducing cardiovascular risk during pregnancy comes too late – the risks have already developed in these patients.
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Similar effect of early, late BP reduction in stroke: CATIS-2
“Antihypertensive treatment can be delayed for at least 7 days following ischemic stroke onset, unless there are severe acute comorbidities that...
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Thrombolysis not necessary in mild nondisabling stroke: ARAMIS
‘We may be doing more harm than good with alteplase in this patient population,’ says expert.
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Drug combo promising in vascular cognitive impairment: LACI-2 trial results
The drugs – isosorbide monoitrate and cilostazol – stabilize endothelial function, which is a new therapeutic target for patients with small-...
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Thrombectomy benefits stroke with large core volumes: SELECT2 trial results
Study findings may change clinical practice and the way in which systems of stroke care are organized.
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STROKE AF at 3 years: High AFib rate after atherosclerotic stroke
Continuous monitoring to detect AFib should be considered in a larger population of stroke patients rather than just those with cryptogenic stroke...
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Brain differences suggest therapeutic targets in Takotsubo
A new study has identified differences in the brain between patients with Takotsubo syndrome, a cardiomyopathy triggered by intense emotional...
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Warfarin best for thrombotic antiphospholipid syndrome?
A vitamin K antagonist such as warfarin, rather than a direct oral anticoagulant, appears to be a better treatment for patients with thrombotic...
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Is thrombolysis safe for stroke patients on DOACs?
“Our results suggest that current guidelines need to be revised to remove the absolute contraindication of thrombolysis in patients on DOACs.”
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Cardiac injury caused by COVID-19 less common than thought
Study examines cardiac MRI scans in 31 patients before and after having COVID-19.
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‘Reassuring’ data on pregnancy with ischemic heart disease
The risk associated with isolated preexisting ischemic heart disease without additional evidence of cardiomyopathy was relatively similar to that...
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The 'Plaque Hypothesis': Focus on vulnerable lesions to cut events
A new strategy is needed that targets unstable plaque in the whole of the coronary arteries, rather than just obstructive lesions, to reduce major...
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Chlorthalidone, HCTZ equally effective in hypertension: DCP published
The Diuretic Comparison Project trial, showing no difference in clinical events between diuretics chlorthalidone and hydrochlorothiazide for...
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Statins tied to lower ICH risk regardless of bleed location
A large new case-control study has shown a reduced risk of both lobar and nonlobar intracerebral hemorrhage with statin use, providing reassurance...