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Antidrug antibody effects compared across RA biologics
The presence of antidrug antibodies was associated with a diminished response to biologic disease-modifying antirheumatic drugs in a prospective...
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Nebulized amphotericin B does not affect aspergillosis exacerbation-free status at 1 year
NAB may delay onset and incidence of aspergillosis exacerbations.
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Pulmonary embolism confers higher mortality long term
The most frequent causes of death were cancer, pulmonary embolism, infections, and cardiovascular events.
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Observation recommended as first-line therapy in select cases of primary spontaneous pneumothorax
Observation was the dominant choice, based on economic modeling showing it to offer both the highest utility and the lowest cost.
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Rehabilitation improves walk test results for post–pulmonary embolism patients with persistent dyspnea
In patients with persistent dyspnea following a pulmonary embolism, rehabilitation should be considered as a treatment option.
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Poor outcomes in fibrotic ILD attributed to nocturnal hypoxemia
In patients with fibrotic interstitial lung disease, nocturnal hypoxemia is associated with poor clinical outcomes.
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Lack of paid sick leave is a barrier to cancer screening
For those with paid sick leave mandates, screening rates are higher.
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New treatments under study for celiac disease
Investigational treatment found to be highly effective in blocking gluten-specific T cells in celiac disease.
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Multiple successive biologic to biosimilar switches deemed safe and effective
Triple switching from infliximab biologic to biosimilar for IBD found no new safety or efficacy concerns.
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Few patients take weight control medications after bariatric surgery
Weight control medications may be needed to prevent weight regain.
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Lack of paid sick leave is a barrier to cancer screening
For those with paid sick leave mandates, screening rates are higher.
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Unprecedented drop seen in early colorectal cancer cases due to aspirin use
The study confirms evidence from 30 years of research that suggests regular aspirin use reduces cancer risk.
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Study of environmental impact of GI endoscopy finds room for improvement
Two months of endoscopy procedures generates two football fields of waste, including plastic, sharps, personal protective equipment, and cleaning...
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Helmet interface for ventilation likely superior in acute hypoxemic respiratory failure
Benefit may also include reduced mortality.
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Can asthma incidence be reduced by attention to sleep disorders?
Early detection and management of sleep disorders could reduce asthma incidence.