Key clinical point: Gout, a common inflammatory disease, is associated with a significantly increased risk for subsequent breast cancer (BC) diagnosis, particularly in young women aged ≤50 years.
Major finding: Gout was significantly associated with an increased risk for subsequent BC in the total population (hazard ratio [HR] 1.17; 95% CI 1.05-1.31), with the risk being more prominent among women who were ≤50 years of age (HR 1.58; 95% CI 1.10-2.27).
Study details: Findings are from a retrospective cohort study including 33,799 women with gout and 33,799 women without gout, of which 4.5% and 3.7% of women were diagnosed with BC during the 10 years of follow-up, respectively.
Disclosures: The lead author was supported by the Philipps-University of Marburg and the University Hospital of Giessen and Marburg. The authors declared no conflicts of interest.
Source: Gremke N et al. Association between gout and subsequent breast cancer: A retrospective cohort study including 67,598 primary care patients in Germany. Breast Cancer Res Treat. 2023;199:545-552 (Apr 18). Doi: 10.1007/s10549-023-06944-w