Pregnant women with obstructive sleep apnea are more likely to experience adverse clinical conditions than are pregnant women who do not have sleep apnea, according to an analysis of over 55 million pregnancy-related hospital discharges from 1998 to 2009.
Women with obstructive sleep apnea (OSA) were nine times more likely to have cardiomyopathy and 8.9 times more likely to have congestive heart failure during pregnancy than were women without OSA, after adjustment for numerous factors, including maternal age and obesity, race/ethnicity, household income, heart disease, hyperlipidemia, and prepregnancy diabetes, reported Dr. Judette M. Louis of the University of South Florida, Tampa, and her associates.
Women with OSA also were more likely to have pulmonary edema (adjusted odds ratio, 7.5), in-hospital mortality (AOR, 5.3), pulmonary embolism and infarction (AOR, 4.5), stroke (AOR, 2.9), and acute renal failure (AOR, 2.7), Dr. Louis and her associates said (Sleep 2014;37:843-9).
The investigators analyzed data on 55,781,965 maternal hospital discharges from 1998 to 2009 in the Agency for Healthcare Research and Quality’s Nationwide Inpatient Sample. The institution of one investigator received a grant from ResMed Inc. and equipment from ResMed and Philips Respironics for use in clinical trials.
