News from the FDA/CDC

CDC reports two new Zika-related pregnancy losses


 

The first pregnancy losses with Zika-related birth defects since last summer were reported March 14 by the Centers for Disease Control and Prevention.

Two new cases were reported to the U.S. Zika Pregnancy Registry between Feb. 21 and March 14 – the time period covered by the most recent release of data from the CDC. That brings the total number of Zika virus–related pregnancy losses to seven since the beginning of 2016 in the 50 states and the District of Columbia, along with 54 liveborn infants with Zika-related birth defects. The CDC stopped reporting adverse pregnancy outcomes in Puerto Rico and the other U.S. territories in early October 2016 because Puerto Rico’s Zika Active Pregnancy Surveillance System is not using the same inclusion criteria as its mainland counterpart.

Cumulative cases of Zika infection in pregnant women
In that same 3-week period from Feb. 21 to March 14, an additional 83 pregnant women with Zika were reported in the states and D.C., along with 138 women in the U.S. territories. So far, 4,980 pregnant women with Zika have been reported in the United States: 1,617 in the states/D.C. (1,228 completed with or without birth defects) and 3,363 in the territories (number completed not reported), the CDC said.

These are not real-time data and reflect only pregnancy outcomes for women with any laboratory evidence of possible Zika virus infection, although it is not known if Zika virus was the cause of the poor outcomes. Zika-related birth defects recorded by the CDC could include microcephaly, calcium deposits in the brain indicating possible brain damage, excess fluid in the brain cavities and surrounding the brain, absent or poorly formed brain structures, abnormal eye development, or other problems resulting from brain damage that affect nerves, muscles, and bones. The pregnancy losses encompass any miscarriage, stillbirth, or termination with evidence of birth defects.

Recommended Reading

Number of US Zika Cases in Pregnant Women up to 537
Clinician Reviews
Rash, Microcephaly Not Always Present With Congenital Zika Syndrome
Clinician Reviews
Zika Coalition Urges Congress to Provide Funding to Combat Zika Virus
Clinician Reviews
Health Officials Investigating Mysterious Zika Infection
Clinician Reviews
To Cut Zika Microcephaly Risk, Delay Pregnancy More Than 9 Months
Clinician Reviews
CDC Updates Zika Guidance for Managing Pregnant Women
Clinician Reviews
Olympic Games Create Novel Opportunity to Study Zika Virus
Clinician Reviews
CDC Confirms First Cases of Locally Transmitted Zika in Continental US
Clinician Reviews
As Zika Looms, Are LARCs the Answer?
Clinician Reviews
Replicative Zika RNA found in brain and placental tissue
Clinician Reviews