Bailey Goodman is an Emergency Medicine PA at Major Hospital in Shelbyville, Indiana. Christopher Roman is an Assistant Professor in the Department of PA Studies at Butler University in Indianapolis.
The diagnosis of EBV can be challenging due to its similarity to group A streptococcal pharyngitis and other viral syndromes. In this case, the development of classic symptoms, along with the morbilliform eruption following administration of an aminopenicillin, was strongly suggestive of this diagnosis. This pairing of EBV infection and aminopenicillin rash does not indicate a penicillin allergy.