5. This patient presented with isolated, grouped, and multiple erythematous to violaceous papules, plaques, or nodules, in an asymmetric distribution.
Diagnosis: B-cell neoplasms with skin involvement can present as primary cutaneous lymphomas or as secondary processes, including specific infiltrates of nodal or extranodal lymphoma or leukemia.5 B-cell lymphomas involving the skin have a distinct clinical appearance, presenting as isolated, grouped, or multiple erythematous to violaceous papules, plaques, or nodules, usually in an asymmetric distribution. B-cell lymphoproliferative diseases simulating rosacea are extremely rare.5 Nevertheless, B-cell lymphoma mimicking rhinophyma has been documented in the literature.5-11
Read more about B-cell neoplasms at The great mimickers of rosacea. Cutis. 2014;94(1):39-45.
Figures 1, 4, 5 reprinted with permission from Cutis. 2014;94(1):39-45; photographs for Figures 4 and 5 courtesy of Marc Silverstein, MD. Figure 2 reprinted with permission from J Fam Pract. 2010 August;59(8):459-462; photograph courtesy of Felix B. Chang, MD. Figure 3 reprinted courtesy of J Fam Pract. 2010 July;59(7):399-401; photograph courtesy of Nikki N. Kim, MD, Heather W. Wickless, MD, MPH.
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5. Barzilai A, Feuerman H, Quaglino P, et al. Cutaneous B-cell neoplasms mimicking granulomatous rosacea or rhinophyma. Arch Dermatol. 2012;148:824-831.
6. Moulonguet I, Ghnassia M, Molina T, et al. Miliarial-type perifollicular B-cell pseudolymphoma (lymphocytoma cutis): a misleading eruption in two women. J Cutan Pathol. 2012;39:1016-1021.
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