By using conservative pain management as a comparator, Dr. Klazen and her colleagues noted, vertebroplasty was tested against “the reference treatment and thus provides the clinician with directly applicable information about how to best treat the patient.”
Dr. Klazen and her colleagues noted that ZonMw and Cook Medical, the sponsors of the study “had no role in study design, data collection, data analysis, data interpretation, writing of the report, or the decision to submit for publication.”