Commentary
The VA Goes Its Own Way on Aducanumab
Why did US Department of Veterans Affairs Pharmacy Benefit Management differ from the FDA and recommend against the use of aduncanumab-avwa for...
Mario F. Mendez, MD, PhDa,b; Rebecca A. Melrose, PhDa,b; Denise G. Feil, MDa,b; Kelsey A. Holiday, PhDa,b; Marianne Hunt, LCSWa; Ali Najafian Jazi, MDa; Sukh L. Lamba, RN-BCa; Michael E. Mahler, MDa,b; Daniel E. Okobi, MD, PhDa,b; Hans F. Von Walter, MDa,b
Correspondence: Mario Mendez (mmendez@ucla.edu)
aVeterans Affairs Greater Los Angeles, California
bUniversity of California, Los Angeles
Author disclosures
The authors report no actual or potential conflicts of interest or outside sources of funding with regard to this article.
Disclaimer
The opinions expressed herein are those of the authors and do not necessarily reflect those of Federal Practitioner, Frontline Medical Communications Inc., the US Government, or any of its agencies.
Ethics
This program description is not classified as research, and thus did not require institutional review board approval.
Before the office visit, the coordinating geriatric psychiatrist triages veterans to neurology, psychiatry, or geriatric physicians based on the clinical presentation, history of neurologic signs or symptoms, BPSD or psychiatric history, functional decline, or comorbid medical illnesses. Although veterans often have overlapping concerns, the triage process aims to coordinate the intake evaluations with the most indicated and available specialist with the intention to notify the other specialists during the transdisciplinary conference.
Referrals to the program occur from many sources, notably from primary care (70.8%), mental health (16.7%), and specialty clinics (12.5%). The clinic also receives referrals from the affiliated Veterans Cognitive Assessment and Management Program, which provides dementia evaluation and support via telehealth screening. This VAGLAHS program services a diverse population of veterans: 87% male; 43% aged > 65 years (75% in our clinic); 51% non-Hispanic White; 19% non-Hispanic African American; 16% Hispanic; 4% Asian; and 1% Native American. This population receives care at regional VA medical centers and community-based outpatient clinics over a wide geographic service area.
The initial standardized assessments by intake or lead physicians includes mental status screening with the Montreal Cognitive Assessment (with certified clinicians), the Neurobehavioral Status Examination for a more detailed assessment of cognitive domains, the Columbia-Suicide Severity Rating Scale, the Patient Health Questionnaire for depression screening, and assessment for impairments in instrumental or basic activities of daily living. This initial evaluation aims to apply clinical guidelines and diagnostic criteria for the differential diagnosis of neurocognitive disorders, determine eligibility for cognitive-enhancing medications and techniques, assess for BPSD and the need for nonpharmacologic or pharmacologic interventions, determine functional status, and evaluate the need for supervision, safety concerns, and evidence of neglect or abuse.
As part of its mission, the clinic is charged with implementing the VA Dementia System of Care (DSOC). The stated goals of the DSOC are to provide individualized person-centered dementia care to help veterans experiencing dementia and their caregivers maintain a positive and optimal quality of life and create an environment where VA medical center staff understand the health care needs of veterans with dementia and their caregivers’ role. As part of this initiative, the clinic includes (1) coordination of care through a SW-DCM; (2)
an education plan disseminating information on early signs of dementia to medical center clinicians; (3) evaluation of veterans and caregivers for VA benefits and care services (Table 2); and (4) collaboration with dementia committees at our VA, Veterans Integrated Service Network, and national levels.Why did US Department of Veterans Affairs Pharmacy Benefit Management differ from the FDA and recommend against the use of aduncanumab-avwa for...
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