Lung Cancer
News
Despite benefits, extended-interval pembro uptake remains low
It’s possible that low uptake could stem from clinicians’ doubts about switching to an extended-interval dose, given that the FDA’s approval was...
Conference Coverage
Weight gain linked to cancer survival in men and women
The finding underscores the need for nutritional support emphasized in 2020 ASCO guidelines.
News
Atezolizumab doubles survival of NSCLC patients with poor performance status
Patients typically excluded from clinical trials because of age or comorbidities had better survival with atezolizumab than single-agent...
Conference Coverage
A farewell to arms? Drug approvals based on single-arm trials can be flawed
Objective responses, not time-dependent survival outcomes, should be endpoints for single-arm trials, with results only used for conditional...
Conference Coverage
Time to cancer diagnoses in U.S. averages 5 months
Diagnosis time varied significantly across tumor types, as well as within the same tumor type.
News
Opioids after lung cancer surgery may up all-cause mortality risk
“New long-term opioid use may be associated with poor long-term survival outcomes, especially in potent opioid users.”
Conference Coverage
In NSCLC, not all EGFR mutations are the same
Patients with the Ex20 insertion may buck trend by responding well to ICIs.
Conference Coverage
In early NSCLC, comorbidities linked to survival
Respiratory and cardiometabolic comorbidities were associated with significantly worse overall survival in lung cancer.
Conference Coverage
‘Smoking gun–level’ evidence found linking air pollution with lung cancer
The finding could lead to strategies for preventing lung cancer in nonsmokers exposed to high levels of foul air.
Conference Coverage
Gene mutations may drive lung cancer in never-smokers
Study hints at mechanistic differences between small cell lung cancer in smokers versus nonsmokers.
