Rare Diseases
News
Pexidartinib gets ODAC nod for tenosynovial giant cell tumor treatment
Missing efficacy data from the pivotal ENLIVEN trial and adverse liver events were points of contention.
Conference Coverage
Baseline imaging recommended in all Merkel cell carcinoma patients
CHICAGO – New data emphasize the need for routine baseline scans in patients with Merkel cell carcinoma.
Conference Coverage
Researchers propose new risk groups for NK-AML
NEWPORT BEACH, CALIF. – Investigators used machine learning algorithms to risk stratify patients with normal karyotype acute myeloid leukemia.
News
FDA approves ivosidenib frontline for certain AML patients
The expanded approval means that ivosidenib can be used first-line for acute myeloid leukemia patients with an IDH1 mutation who are not eligible...
News
Idelalisib shows long-term safety, efficacy for relapsed CLL
The long-term data confirm that the addition of idelalisib to rituximab significantly improves outcomes for patients with relapsed CLL. However,...
Conference Coverage
Three-drug regimen shows promise for refractory primary biliary cholangitis
VIENNA – Combining ursodeoxycholic acid, obeticholic acid, and bezafibrate showed efficacy and tolerability for the toughest cases.
Conference Coverage
High-dose MTX-based chemo is well tolerated in older PCNSL patients
GLASGOW – A retrospective, real-world study suggests that older, fit patients can tolerate an intensive treatment regiment for primary central...
News
Ixekizumab posts positive results in phase 3 nr-axSpA trial
The safety profile of ixekizumab was broadly similar to what has been seen in previous phase 3 trials, Eli Lilly reports.
News
Does Residential Mobility Affect Childhood Leukemia?
A new study looks into the correlation between the dwelling of children and childhood leukemia.
Conference Coverage
Creating CAR T-cell therapies for T-cell malignancies
NEWPORT BEACH, CALIF. – Dr. John F. DiPersio discusses preclinical research testing CAR T-cell therapies in T-cell malignancies.