Anemia
News
Team uses CRISPR to turn on fetal hemoglobin
Researchers have used CRISPR-Cas9 gene editing to reproduce naturally occurring mutations that boost the production of fetal hemoglobin. The...
Conference Coverage
Most patients off transfusions after gene therapy for thalassemia
SALT LAKE CITY – As the vector copy number goes up, so does the likelihood of stopping transfusions.
News
Drug approved to treat all adults with iron deficiency
The European Commission (EC) has extended the approved indication of ferric maltol (Feraccru) to include treatment of all adults with iron...
News
Amgen withdraws application for darbepoetin alfa
Amgen has withdrawn its application to expand the existing marketing authorization for darbepoetin alfa (Aranesp), according to the European...
Conference Coverage
Manufactured graft deemed safe in blood cancer patients
LISBON—Phase 1 results suggest a programmed cellular therapy is safe for use in patients with hematologic malignancies. The therapy, ProTmune, is...
News
Severe anemia in pregnancy may double risk of death
Pregnant women with severe anemia are twice as likely as those without it to die during or shortly after pregnancy, according to research...
CME
The Long and Winding Road: PTCL 10 Years from Now
Conference Coverage
Nonmyeloablative conditioning gets a radiation boost for severe hemoglobinopathies
SALT LAKE CITY – Doubling total body irradiation reduced graft rejection without increasing toxicity for patients with sickle cell disease or beta...
News
Drug nets orphan designation for beta-thalassemia
The US Food and Drug Administration (FDA) has granted orphan drug designation to PTG-300, a subcutaneous injectable hepcidin mimetic, for the...
Latest News
HCT-CI score may predict mortality for nonmalignant disease
SALT LAKE CITY – The Hematopoietic Cell Transplantation Comorbidity Index (HCT-CI) is useful in hematologic malignancies, but it may also be...
Conference Coverage
HSCT approach provides ‘excellent’ survival in FA
SALT LAKE CITY—A “risk-adjusted” approach leads to “excellent” survival in patients with Fanconi anemia (FA) undergoing alternative donor...