Neuroendocrine tumors are a rare type of neoplasms that comprise only 0.5% of all malignancies.1 They usually arise from the gastrointestinal tract and the lung.1,2 Neuroendocrine carcinoma of the head and neck is a relatively rare malignancy described in the literature. The larynx is the most commonly affected region of the head and neck.3,4 Nevertheless, small-cell carcinoma comprises only 0.5% of all laryngeal cancers.5 Neuroendocrine carcinoma of the larynx carries variable prognosis depending on the histological subtype.6 Typical carcinoid rarely metastasizes, but atypical carcinoid and small-cell carcinoma have high rates of metastasis, usually in the lung and liver.2 Cutaneous metastasis from neuroendocrine carcinoma is an extremely rare entity, with only few cases reported in the English literature.7,8 We report the case of an elderly man with recurrent laryngeal neuroendocrine carcinoma with metastasis to the eyelid.
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