Primary bladder adenocarcinoma is an epithelial malignancy with pure glandular differentiation, without evidence of typical urothelial (transitional cell) carcinoma. PBA is rare, accounting for 0.5%-2% of all malignant bladder neoplasms, and it is seen more frequently in men than in women and is commonly diagnosed in the sixth decade of life.1-3 Clinical presentation includes hematuria and symptoms of bladder irritation.2
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