Conference Coverage

New drugs provide new options in HCC


 

REPORTING FROM DIGESTIVE DISEASES: NEW ADVANCES


Dr. Pyrsopoulos highlighted another checkpoint inhibitor, known as BGB-A317, or tislelizumab. In January, BeiGene announced the initiation of a global phase 3 trial of this anti-PD-1 antibody versus sorafenib as first-line treatment of patients with unresectable HCC.

Although cancer immunotherapy holds great promise for HCC and other cancers, the treatments are associated with unique immune-related adverse events (irAEs) including immune-related hepatitis that may require corticosteroid treatment, according to Dr. Pyrsopoulos.

Dr. Pyrsopoulos reported disclosures related to AbbVie, Bayer, Genfit, Gilead Sciences, Hologic, Merck, Prometheus, Shire, and Vital Therapies.

Global Academy for Medical Education and this news organization are owned by the same company.

Pages

Recommended Reading

DNA repair gene mutations predict response to anti–PD-1/PD-L1 in urothelial cancer
MDedge Hematology and Oncology
Cancer groups offer guidance on immune-related adverse events
MDedge Hematology and Oncology
Chemotherapy, metabolic pathway may affect CAR T-cell potential
MDedge Hematology and Oncology
HDAC inhibition may boost immune therapy efficacy in breast cancer
MDedge Hematology and Oncology
Checkpoint inhibition less toxic than antiangiogenic therapy in NSCLC
MDedge Hematology and Oncology
Nivolumab helps some with advanced NSCLC reach 5-year mark
MDedge Hematology and Oncology
Surgery after immunotherapy effective in advanced melanoma
MDedge Hematology and Oncology
Blinatumomab triggers complete MRD response in ALL
MDedge Hematology and Oncology
KEYNOTE-054: Adjuvant pembrolizumab beat placebo in high-risk resected melanoma
MDedge Hematology and Oncology
Early results favorable for combo TLR9 agonist + pembro in advanced melanoma
MDedge Hematology and Oncology