In his monthly podcast for The Journal of Community and Supportive Oncology for October, David Henry examines two research articles that focus on patient-provider communication: one article looks at patient and provider concordance on symptoms and the other discusses the informational needs and the quality of life of patients after being diagnosed with metastatic breast cancer. Two other original research articles on weight change in breast cancer patients on third-generation adjuvant chemotherapy and the quality of supportive care in patients with advanced lung cancer in the Veterans Health Administration plus a Case Report about breast cancer with brain metastases in pregnancy round off the clinical portion of the line-up. A feature article details the current state of biomarker development and challenges that temper their clinical potential.