Cellular Therapy
Conference Coverage
Chronic GVHD linked to fivefold increase in squamous cell skin carcinomas
PORTLAND – Nonmelanoma skin cancers may be a higher risk with GVHD than has previously been quantified.
Conference Coverage
Cord blood/placental cell combo induces rapid immune recovery
MONTREAL – The probability of 1-year survival in children with severe diseases requiring stem cell transplants was 81%.
From the Journals
Optimum antithymocyte globulin exposure after HTC affects survival
Optimum antithymocyte globulin exposure after allogeneic hemopoietic cell transplantation plays an important role in survival.
Conference Coverage
Biomarker algorithm sharpens GVHD treatment outcomes prediction
ORLANDO – A biomarker algorithm was better than was clinical response at predicting outcomes after 1 week of systemic steroid treatment for graft-...
Conference Coverage
Reduced-intensity conditioning may not preserve fertility in young girls after bone marrow transplant
ORLANDO – Talking with a child who is about to undertake chemo about preserving her fertility may be the furthest thing from everyone’s mind, but...
Conference Coverage
Three factors linked to rhinovirus pneumonia in HCT patients
Higher levels of steroid use, a low white blood cell count, and a low monocyte count increased risk of lower rhinovirus respiratory tract...
From the Journals
Transplantation plus VRD tops VRD alone in myeloma
High-dose chemotherapy and autologous stem cell transplantation plus bortezomib, lenalidomide, and dexamethasone (VRD) outperformed consolidation...
From the Journals
Cell sheet transplantation improves ischemic cardiomyopathy at 1 year
Affixing a sheet of autologous stem cells directly onto the left ventricle led to improvements in ICM out to 1 year.
Conference Coverage
Off-the-shelf T cells an option for post-HCT viral infections
ORLANDO – Banked donor T cell infusions might prove an alternative to donor-derived virus-specific T cells for patients who have drug-refractory...
Conference Coverage
Tocilizumab shows promise for GVHD prevention
ORLANDO – The interleuken-6 receptor blocker tocilizumab showed promising activity for preventing graft-versus-host disease when added to standard...
Conference Coverage
CAR designers report high B-cell cancer response rates
A CAR-T cell construct consisting of autologous CD4-positive and CD-8 positive T cells delivered in a single infusion was associated with high...