Gastroenterology
News
Immunomodulator MGN1703 Cuts Risk of Colorectal Cancer Progressing
Major Finding: Maintenance therapy with MGN1703 reduced the risk of progression by 47% vs. placebo (HR, 0.53; P = .06).Data Source: Phase II/III...
News
Less Liver Cancer in HCV Patients Given Antiviral Therapy
Major Finding: Antiviral therapy for hepatitis C carried a relative risk of 0.53 for developing hepatocellular carcinoma, compared with no...
News
Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy
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Screening All Colorectal Tumors Detects Lynch Syndrome Best
Major Finding: Universal screening of colorectal cancers’ DNA for MMR abnormalities had a sensitivity of 100% and a specificity of 93% in...
News
Cetuximab Fails First-Line in Gastric Cancer
Major Findings: Median progression-free survival was 4.4 vs.
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Gefitinib Offers Palliative Care in Advanced Esophageal Cancer
Major Finding: Median overall survival was 3.73 months with gefitinib vs. 3.60 months with placebo (P = .285).Data Source: Data are from a phase...
Article
Cetuximab plus FOLFIRI in first-line treatment of KRAS mutation-negative, EGFR-positive metastatic colorectal cancer
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FDA Approves Regorafenib for Metastatic Colorectal Cancer
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Two Common Genetic Variants Linked to Barrett's Esophagus
Major Finding: The rs9257809 SNP on chromosome 6p21 and the rs9936833 SNP on chromosome 16q24 both were strongly associated with an increased risk...
News
Long-Term Follow-Up Warranted After Gastric MALT Lymphoma Remission
Major Finding: Of 120 participants, 96 (80%) achieved complete remission of gastric MALT lymphoma, and 80% of them (77/96) remained disease free....