GI Oncology
From the Journals
Staying up to date on screening may cut risk of death from CRC
Staying up to date on screening was associated with a 62% decrease in the odds of dying from colorectal cancer.
Conference Coverage
Risk of cancer in NAFLD is 91% higher than in control subjects
SAN FRANCISCO – The observed increase is highest in gastrointestinal cancer subjects.
News
FDA approves pembrolizumab for sorafenib-intolerant HCC patients
Approval was based on an objective response rate of 17% in KEYNOTE-224, a single-arm trial of 104 patients with hepatocellular carcinoma who were...
From the Journals
No difference for blacks vs. whites in precancerous colorectal neoplasm prevalence: A meta-analysis
Investigators suggest that the age at which screening starts need not differ based on race.
Conference Coverage
Increased incidence of GI, colorectal cancers seen in young, obese patients
PHILADELPHIA – Obese patients of all ages had higher rates of colorectal cancer resections and differing age ranges had higher rates of other GI...
From the Journals
Myeloperoxidase elevated in HCV-related liver cancer
Marked expression of myeloperoxidase is associated with the pathogenesis of HCV-related hepatocellular carcinoma.
From the Journals
Proximal adenoma location does not predict high-grade dysplasia
The odds of high-grade dysplasia were slightly lower for proximal versus distal adenomas.
Guidelines
Guideline: Early screening warranted if family history of nonhereditary colorectal cancer
Initial screening colonoscopy should occur at age 40-50 years, or 10 years before the age of the earliest-diagnosed first-degree relative.
Case-Based Review
Management of Metastatic Gastric Cancer
From the Journals
Proinflammatory diet linked to colorectal cancer testing positive for Fusobacterium nucleatum
Dietary scores in the highest tertile correlated with significantly increased risk (P = .03).
From the Journals
Commentary: Composite risk, not age, is key for timing first colorectal cancer screening
Age may not be the colorectal cancer screening issue.