GI Oncology
From the Journals
Age should not be a barrier to aggressive esophageal cancer treatment
Comorbidities, fitness are what matters.
From the Journals
ASCO announces new advanced liver cancer guidelines
The American Society of Clinical Oncology announced new guidelines for systemic therapy of advanced hepatocellular carcinoma.
Article
Nanoparticle encapsulation may unlock HCC therapy
The investigators turned to nanoparticles, which accumulate in tumor tissue more than healthy tissue, thereby limiting off-target toxicity.
From the Journals
Color-imaging endoscopy improves detection of upper GI cancer
Neoplastic lesions were detected in 60 patients (8%) with LCI versus 36 patients (4.8%) with WLI, which translated to a 1.67 times higher rate of...
Article
Study reveals how aspirin may inhibit colorectal cancer
Aspirin rescued a proneoplastic intestinal phenotype, reduced stem cell expression and function, and increased the expression of an important Wnt...
From the Journals
Younger adults present with more advanced esophageal adenocarcinoma
The incidence of esophageal adenocarcinoma has risen threefold over the past 4 decades among patients younger than 50 years.
From the Journals
PDAC: Tumor reduction after neoadjuvant therapy may predict postsurgical survival
A 47% or more reduction in tumor size between endoscopic ultrasound and surgery predicted 3- and 5-year survival in pancreatic ductal...
From the Journals
Geography and behaviors linked to early-onset colorectal cancer survival in U.S. women
Physical inactivity and lower fertility correlate modestly with early-onset colorectal cancer mortality in women.
From the Journals
Pembrolizumab ‘preferred choice’ in MSI-H/dMMR metastatic CRC
Compared with chemotherapy, pembrolizumab doubled progression-free survival and improved the overall response rate in this patient population.
From the Journals
Hemochromatosis variants may confer 10-fold higher risk of liver cancer
Men of European ancestry had a greater risk of liver cancer and death if they had HFE variants.
Conference Coverage
Rapid relief of opioid-induced constipation with MNTX
Subcutaneously administered, peripherally acting mu-opioid receptor antagonist, relieves opioid-induced constipation in both chronic, noncancer-...