Leukemia, Myelodysplasia, Transplantation
News
Drug gets orphan designation for MDS
The drug, CPI-613, targets metabolic changes that are thought to occur in many cancer cells. It has demonstrated activity and tolerability in a...
News
Cranial radiotherapy for acute lymphoblastic leukemia linked to impaired neurocognition
Major finding: Compared with controls, survivors who had cranial radiotherapy had significant reductions in white matter integrity and lower...
News
Natural killer cell protein affects pediatric stem cell transplant survival
Major finding: Compared with patients who received donor grafts with two cysteine-containing alleles, the hazard ratio for the risk of death was 0...
Article
Chimeric antigen receptor-modified T cells in acute lymphoblastic leukemia
Article
C. albicans appendicitis in a neutropenic patient after induction chemotherapy
Community Translations
Omacetaxine for chronic or accelerated phase CML in patients with resistance or intolerance to TKIs
News
Splenectomy mortality risk similar for malignant and benign disease
Major finding: Following elective splenectomy, the rate of overall complications was significantly higher for patients with malignant vs. benign...
News
New biomarker predicts treatment-resistant GVHD
Major finding: Patients with high ST2 levels were 2.3 times more likely than those with low ST2 levels to develop treatment-resistant GVHD, and 3....
News
Revised IPSS bests other systems for predicting MDS outcomes
Major finding: Compared with counterparts having scores that put them into the IPSS-R intermediate-risk group, patients having scores that put...
News
VTE rate triples in pediatric cancer survivors
Major finding: Pediatric cancer survivors had a 3.4-fold increased rate of venous thromboembolism during follow-up, compared with controls.Data...
News
CD123 differentiates acute GVHD from infections, drug reactions
Major finding: Among 38 colonic endoscopy samples from patients with acute GVHD, 25 (66%) were positive on CD123 staining.