Neuro-oncology
News
Good survival rates with temozolomide CRT for high-risk, low-grade gliomas
Major finding: With temozolomide chemoradiotherapy, 3-year overall survival was 73% for patients with low-grade gliomas and three or more risk...
Conference Coverage
Donepezil fails to improve cognition after brain irradiation
Major finding: There were no significant differences between donepezil or placebo in either cognitive composite scores after 12 or 24 weeks of...
News
Frontline bevacizumab fails to boost glioblastoma survival in key trials
Major finding: Median overall survival for those assigned to radiation, temozolomide, and placebo was 16.1 months, vs.
News
Bevacizumab plus irinotecan beats temozolomide in stalling glioblastoma
Major finding: The 6-month progression-free survival 6 months after randomization was 79.6% for patients treated with bevacizumab and irinotecan...
News
Manage most SEGAs with rapamycin analogs, not surgery
Major finding: Rapamycin analogs shrink SEGA tumors by more than 50% in a majority of children, and obviate the need for surgery. Data source:...
News
Duloxetine reduces chemo-induced neuropathy
Major finding: Study subjects were 2.4 times more likely to experience a 50% pain reduction while taking duloxetine than while taking placebo.Data...
News
'Chemobrain' starts before chemotherapy in breast cancer study
Major Finding: Women scheduled to undergo chemotherapy after surgery for breast cancer were significantly more likely to show low brain activation...
News
PET/CT Pinpoints Physiological Evidence of Chemo Brain
Major Finding: Statistically significant declines in glucose metabolism were observed post chemotherapy in the superior medial frontal gyrus as a...
News
Early Surgery Yields Survival Benefit for Low-Grade Gliomas
Major Finding: Overall mortality was 52% with watchful waiting and 32% with early resection; median survival was 5.9 years in the first group but...
News
Memantine Protects Cognitive Function After Whole Brain Irradiation
Major Finding: Cancer patients with brain metastases had a 17% relative reduction in cognitive decline after whole brain radiation if they took...
News
Can Lapatinib Prevent Brain Metastases from Breast Cancer? Data 'Inconclusive'
Major Findings: The primary end point of CNS as first site of relapse was no different comparing lapatinib-capecitabine (3%) vs. trastuzumab-...