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Raspberries Implicated in Outbreaks of Norovirus


 

ATLANTA — As summer approaches, it may be wise to be wary of berries. Five norovirus outbreaks affecting several hundred people in Denmark in 2005 were traced to a single batch of contaminated frozen raspberries, Dr. Gerhard Falkenhorst reported at the International Conference on Emerging Infectious Diseases.

The first cases of illness in each outbreak appeared within 24 hours after the patients ate a raspberry dessert, and norovirus was detected in stool samples from all but one outbreak, said Dr. Falkenhorst, of the Statens Serum Institut, Copenhagen.

The outbreaks occurred between May and September 2005, and all of them involved mass catering settings—one hospital, one “meals-on-wheels” service, one restaurant, and two nursing homes. All of the outbreaks involved desserts made with frozen raspberries.

The first outbreak occurred in a hospital, and both patients and staff members reported acute gastroenteritis. Ultimately, nearly 450 cases occurred in this outbreak. Several cases occurred simultaneously, which suggested a foodborne cause, and norovirus was discovered in food tracings that implicated a dessert made with raspberries that were part of a single, large shipment from Poland.

Although the supplier began a voluntary recall of the shipment, the affected raspberries had already been sent to other clients and were linked to several other outbreaks.

The second outbreak affected about 70 residents and staff members at a nursing home the day after a raspberry dessert had been served, and the third outbreak struck several hundred clients of a “meals-on-wheels” service, which reported diarrhea and vomiting among its clients within 2 days after they had received raspberry desserts. The attack rate was especially high among patients aged 85 years and older, Dr. Falkenhorst noted.

A case-control study confirmed that all the desserts associated with the outbreaks were prepared with crushed, frozen raspberries from the same batch imported from Poland. The same norovirus genogroup (II.7) was identified in 24 of 54 stool samples from one outbreak and 9 of 11 stool samples from the second outbreak. Also, norovirus genogroup II.4 was found in 15 of 15 samples from a third outbreak and genogroup II.b was found in 4 of 8 samples from another outbreak.

This series is the first time several norovirus strains were found in stool samples involving the same raspberry vehicle, Dr. Falkenhorst noted.

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