Early Clopidogrel Can Improve MI Outcome : Benefit seen in patients with ST-segment elevation who undergo percutaneous coronary interventions.

“I think that there is evidence that the 600-mg dose is effective and safe, especially if given less than 6 hours before PCI. If it's going to be 6 or more hours before PCI is done, then I'd use 300 mg,” Dr. Sabatine told this newspaper.