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Neisseria gonorrhoeae Now Sidesteps Fluoroquinolones


 

The CDC's new guidelines include these recommendations:

Uncomplicated gonococcal infections of the cervix, urethra, and rectum. Recommended regimens: Ceftriaxone 125 mg in a single dose IM, or cefixime 400 mg in a single oral dose, plus treatment for chlamydia if chlamydial infection is not ruled out. Alternative regimens: Spectinomycin (not available in the United States) 2 g in a single dose IM or cephalosporin single-dose regimens (including ceftizoxime 500 mg IM, or cefoxitin 2 g IM administered with probenecid 1 g orally, or cefotaxime 500 mg IM).

Uncomplicated gonococcal infections of the pharynx. Recommended regimens: Ceftriaxone 125 mg in a single dose IM, plus treatment for chlamydia if chlamydial infection is not ruled out.

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