Among the 1,944 patients in the substudy, the incidence of cardiovascular death or heart failure hospitalization at 12 months was inversely associated with KCCQ scores.
Dr. Ekman pointed out that recommended therapies with survival benefits like beta blockers have no impact on health-related quality of life, while some therapies that improve quality of life like inotropic agents do not improve survival.
Dr. Tardif and Dr. Ekman reported that all the study’s authors have received fees, research grants or both from the study sponsor, Servier. Dr. Pieske reported having no relevant disclosures.