CHAMPION "is a strikingly important study. It has global implications for the way we treat patients. The rapid on and off deals with a lot of clinical scenarios we face all the time," said Dr. Martin Leon, an interventionalist at Columbia University.
"Sometimes we need to wait 5-7 days before a patient can go to surgery because of the increased risk of bleeding" following treatment with an oral antiplatelet drug, said Dr. Cindy Grines, an interventionalist at Detroit Medical Center. "This will have a huge impact."
Dr. Bhatt, Dr. Mehran, and Dr. Grines reported financial ties with several pharmaceutical companies, including the Medicines Company, which is developing cangrelor. Dr. Harrington and Dr. Stone reported ties with numerous drug companies, including receiving a research grant from the Medicines Company. Dr. Leon disclosed having ties to two device makers but no pharmaceutical companies.