Key clinical point: Poor sleep and higher stress level is associated with a higher rate of headache recurrence over next 6 weeks in patients with episodic migraine.
Major finding: Poor sleep quality was associated with a 22% higher rate of headache recurrence (adjusted hazard ratio [aHR], 1.22; 95% confidence interval [95% CI], 1.02-1.46), and the combination of poor sleep and moderate/high stress vs. good sleep and low stress was associated with a 31% higher rate of headache recurrence (aHR, 1.31; 95% CI, 1.05-1.65).
Study details: Findings are from a priori secondary analysis of a prospective cohort study of 98 patients with episodic migraine.
Disclosures: The work was funded by the National Institute of Neurological Disorders and Stroke, the American Sleep Medicine Foundation, the Harvard Clinical and Translational Science Center, and Harvard University and its affiliated academic health care centers. Dr. SM Bertisch reported receiving research support from and serving as a consultant for various sources. All other authors declared no financial conflicts of interest.
Source: Vgontzas A et al. Headache. 2021 Mar 22. doi: 10.1111/head.14105.