Conference Coverage

VIDEO: Adverse ventilation effect means rethinking Cheyne-Stokes respiration


 

AT THE ESC CONGRESS 2015

References

LONDON – The management of Cheyne-Stokes respiration in patients with heart failure with reduced ejection fraction needs to be reconsidered following the troubling outcome of a major trial that tested adaptive servo-ventilation as treatment for this symptom, Dr. Lars Køber commented during an interview at the annual congress of the European Society of Cardiology.

Cheyne-Stokes respiration, a form of central sleep apnea, differs from obstructive sleep apnea in that heart failure patients do not seem to derive symptomatic benefit from adaptive servo-ventilation treatment, but “physicians have thought they could treat this sleep apnea [with ventilation] and it would change prognosis,” said Dr. Køber. “Treatment of sleep apnea is possible, so physicians had started doing it.” But instead of helping patients, the trial results strongly suggested that patients were harmed by treatment, which was significantly linked with increased rates of both all-cause and cardiovascular mortality (N Engl J Med. 2015 Sep 1. doi: 10.1056/NEJMoa1506459).

In our video interview, Dr. Køber, professor of cardiology at Rigshospitalet and the University of Copenhagen, discusses the results and what the findings imply for future treatment.

The video associated with this article is no longer available on this site. Please view all of our videos on the MDedge YouTube channel.

mzoler@frontlinemedcom.com

On Twitter @mitchelzoler

Recommended Reading

Aspirin, Warfarin Show Equal Heart Failure Efficacy
MDedge Neurology
FDA Reviewing Possible Heart Failure Risk with Pramipexole
MDedge Neurology
Palliative care shortens ICU, hospital stays, review data show
MDedge Neurology
Registry renal denervation skews from resistant hypertension
MDedge Neurology
Frozen or powdered? Anticoagulation options in trauma are expanding
MDedge Neurology
FDA finalizes medical device cybersecurity guidance
MDedge Neurology
Key definitions, data standards established for CV endpoints
MDedge Neurology
Anticipation runs high for coming megatrials in general cardiology
MDedge Neurology
Novel oral anticoagulants best warfarin for AF in heart failure
MDedge Neurology
Inpatient mortality down for high-volume conditions
MDedge Neurology

Related Articles