Literature Review

Abstinence and Heavy Drinking May Increase Dementia Risk


 

Some Questions Answered, Some Questions Remain

This study fills gaps in knowledge, “but we should remain cautious and not change current recommendations on alcohol use based solely on epidemiologic studies,” said Sevil Yasar, MD, PhD, in a related editorial. Dr. Yasar is an Associate Professor of Medicine at Johns Hopkins School of Medicine in Baltimore.

Dr. Yasar called for further studies and, ideally, a government-funded randomized clinical trial with close monitoring of adverse outcomes to answer pressing questions about the possible protective effects of light-to-moderate alcohol use on risk of dementia and about the mediating role of cardiovascular disease. “Alcohol consumption of one to 14 units per week may benefit brain health; however, alcohol choices must take into account all associated risks, including liver disease and cancer.”

Suggested Reading

Sabia S, Fayosse A, Dumurgier J, et al. Alcohol consumption and risk of dementia: 23 year follow-up of Whitehall II cohort study. BMJ. 2018;362:k2927.

Yasar S. Relation between alcohol consumption in midlife and dementia in late life. BMJ. 2018;362:k3164.

Pages

Recommended Reading

New PET imaging agent shows loss of synaptic density in Alzheimer’s brains
MDedge Neurology
Dementia epidemiology in LGB community examined for first time
MDedge Neurology
Gates Foundation, Lauder family launch $30 million Alzheimer’s biomarker search
MDedge Neurology
Pregnancy and years of reproductive capability linked to dementia risk
MDedge Neurology
Mild cognitive impairment risk slashed by 19% in SPRINT MIND
MDedge Neurology
Monoclonal antibody slowed cognitive decline, cleared Alzheimer’s plaques in phase 2 trial
MDedge Neurology
Blood pressure meds cut cognitive impairment risk
MDedge Neurology
Heather Snyder, PhD
MDedge Neurology
Alzheimer’s trial design problem throws a wrench in promising BAN2401 results
MDedge Neurology
Antibody cleared amyloid plaques, slowed cognitive decline
MDedge Neurology

Related Articles