Genomic Research Could Yield Preventive Therapies for SUDEP

Adenosine receptors may be another target for intervention. When researchers blocked adenosine deaminase or adenosine kinase in mouse models of SUDEP, the mice’s seizures ended more quickly, but the mice had an increased risk of death. Treatment at the onset of the seizure, rather than during the seizure, with an adenosine receptor antagonist may improve survival, concluded Dr. Goldman.

—Erik Greb
Senior Associate Editor