Differences in follow-up did not appear to bias the results. Among the patients with hippocampal abnormalities at baseline, there were no significant differences between patients with or without MRI follow-up for status epilepticus duration, T2 scores, presence of developmental delay, focal status, and abnormal acute EEG. However, in both patients with hippocampal abnormalities at baseline and in the FSE cohort overall, patients with multiple conditions that affect well-being, such as developmental delay, epilepsy, or recurrent status epilepticus, seemed to be more likely to undergo follow-up MRI.
The study was supported by grants from the National Institute of Neurological Disorders and Stroke and the Eunice Kennedy Shriver National Institute of Child Health and Human Development. No financial disclosures were reported.