Substantial progress has been made in regard to the identification of effective treatments for cognitive impairments in persons with multiple sclerosis (MS), according to a recent updated literature review from 2007 through 2016. Searches of literature were conducted using combinations of the following terms: attention, awareness, cognition, cognitive, communication, executive, executive function, language, learning, memory, perception, problem solving, reasoning, rehabilitation, remediation, training, processing speed, and working memory. 129 articles were identified and underwent initial screening; 59 articles were selected for inclusion after initial screening; 19 studies were excluded after further detailed review; and 40 studies were fully reviewed and evaluated. Investigators found:

• The review yielded 6 class I studies, 10 class II studies, and 24 class III studies.
• 1 intervention in the area of verbal learning and memory received support for a practice standard, 2 computer programs received support as practice guidelines (in the area of attention and multi-cognitive domains), and several studies provided support for 5 practice options in the domains of attention and learning and memory.