Literature Review

Deciphering the Significance of Generalized Periodic Discharges

GPD-related mortality was linked to poor mental status, cardiac arrest, COPD.


 

Dementia, poor mental status during electroencephalogram (EEG), chronic focal abnormalities on neuroimaging, cardiac arrest, and chronic obstructive pulmonary disease (COPD) were independently associated with increased in-hospital mortality in patients with generalized periodic discharges (GPDs), according to an analysis of 113 patients at 3 hospitals. To determine the prognostic significance of GPDs observed during EEGs, Jadeja et al reviewed EEG tracings of the patients, of whom there were 60 inpatient deaths (53.1%).

Jadeja N, Zarnegar R, Legatt AD. Clinical outcomes in patients with generalized periodic discharges. Seizure. 2017; 45:114-118.

Recommended Reading

Changes in Pre-Seizure Interictal Spike Shape Repeated During Post-Seizure Sleep
Epilepsy Resource Center
NORSE: Cryptogenic New-Onset Refractory Status Epilepticus
Epilepsy Resource Center
Half of Patients With Epilepsy Do Not Receive Medication Soon Enough
Epilepsy Resource Center
Restless Leg Syndrome More Common in Temporal Lobe Epilepsy
Epilepsy Resource Center
Mitigating Stress Levels May Impact Seizures
Epilepsy Resource Center
Epilepsy-Related Deaths Have Increased Over the Years
Epilepsy Resource Center
Self-Management Skills Vary Among People with Epilepsy
Epilepsy Resource Center
Epilepsy Research Requires Better Selection Algorithms
Epilepsy Resource Center
Resective Epilepsy Surgery May Be Beneficial in Patients 70 and Older
Epilepsy Resource Center
Neuropsychiatric Strategies May Benefit Patients With Refractory Epilepsy
Epilepsy Resource Center